Severity of central sensitization in patients with chronic low back pain
Background: Low back pain develops into Chronic Low Back Pain (CLBP) due to the contribution of various psychosocial factors in approximately 10-20% of all patients. CLBP is classified into three groups namely neuropathic, nociceptive and central sensitization (CS). CS results in pain due to hyper-responsive nociceptive neurons and recruitment of sub-threshold or normal stimuli.
Objective: To determine the frequency of central sensitization in patients with chronic low back pain
Methods: A descriptive cross-sectional observational study was conducted on 388 patients with CLBP, aged between 18 to 44 years, using non-probability convenient sampling. Patients were recruited from Ghurki Trust and Teaching Hospital, whereas, adults with a history of spinal surgery within the last 12 months, use of NSAIDs/analgesics, and coexisting neurological, respiratory, cardiac, or rheumatic disorder were excluded. The participants were requested to fill the Central Sensitization Inventory (CSI) questionnaire which has a test-retest reliability of 0.817.
Results: Out of 388 participants, 22.7% (n=88) of the participants demonstrated subclinical central sensitization. Mild central sensitization was reported by 33.0% (n=128) participants, 20.6% (n=80) demonstrated moderate central sensitization scores on the CSI. Whereas, severe central sensitization was found in 13.4% (n=52) participants and 10.3% (n=40) of the participants reported extreme central sensitization category based on their scores on the CSI.
Conclusion: Mild central sensitization was reported frequently among patients with chronic low back pain.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All Articles are made available under a Creative Commons "Attribution-NonCommercial 4.0 International" license. Copyrights on any open-access article published by the Foundation University Journal of Rehabilitation Sciences (FUJRS) are retained by the author(s). FUJRS is an open-access journal that allows free access to its published articles, in addition, to copy and use for research and academic purposes; provided the article is correctly cited. FUJRS does not allow commercial use of the articles published in FUJRS. All articles published represent the view of the author(s) and do not reflect the official policy of FUJRS.