Comparison of rate of Infection between Antibiotic and Non-Antibiotic Groups in Patients Undergoing Non-Surgical Exodontia
Objective: To compare the infection rate between antibiotic and non-antibiotic groups in patients undergoing non-surgical exodontia.
Materials and Methods: After meeting the inclusion and exclusion criteria, 1760 patients (880 in each group) requiring non-surgical exodontia were enrolled. Informed consent and demographic details were taken. The distribution of patients was done into two groups: A and B with the help of the chance method. Patients in the A group were given no antibiotics and only analgesics (Tab. Ibuprofen 400mg) every eight hours for 3 days postoperatively and the patients in the B group were given antibiotics (Tab. Amoxicillin 500 mg with Clavulanic acid 125mg) 8 hourly and analgesics (Tab. Ibuprofen 400mg) 8 hourly for 3 days postoperatively. The recall visit was planned for the 3rd postoperative day. On the follow-up visit, infection signs' evaluation in terms of the presence or absence of purulent discharge was done.
Results: Mean age of the patients in the antibiotic group came out to be 27.85±7.48 years, while the mean age calculated for the patients included in the non-antibiotic group remained 27.50±7.27 years. The ratio between male and female patients was 0.9:1. In the antibiotic group, the purulent discharge was found in 3 (0.34%) patients, whereas in patients without the antibiotic group the purulent discharge was present in 5 (0.57%) patients (p-value=0.726).
Conclusion: This study concludes that there appears not much difference between the antibiotics and that of
the non-antibiotic group in terms of developing an infection after routine exodontia therefore antibiotics are not warranted after non-surgical exodontia.
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